Primary importance
- Drink boiled and filtered water
- Clean raw fruits and vegetables adequately before consumption
- Proper hand washing
- TMP-SMX given as prophylaxis against PCP pneumonia will also prevent against recurrent bacterial infections
Vaccination:
- Hib and pneumococcal vaccination in HIV infected children less than 5 years of age will be highly recommended.
- Administer all the routine bacterial vaccines.
Secondary prevention
- TMP-SMX prophylaxis for patients with recurrent bacterial infections. [Recurrent bacterial infections is defined as 2 or more systemic bacterial infections including septicemia, meningitis, pneumonia and osteomyelitis that occur within a two-year period]
- Intravenous Immunoglobulin [IVIg] at 400 mg/kg monthly for children with hypogammaglobulinemia if there are recurrent bacterial infections inspite of TMP-SMX prophylaxis.
Drugs & Dosage for of TMP-SMX
Drugs |
Dosage |
TMP/SMX
|
- 150 mg of TMP m2/day PO BD on alternate day
- 5 mg/kg of TMP/day PO HS daily
|
|