ISSN 0973-9289
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PREVENTION OF BACTERIAL INFECTIONS
Primary importance
  • Drink boiled and filtered water

  • Clean raw fruits and vegetables adequately before consumption

  • Proper hand washing

  • TMP-SMX given as prophylaxis against PCP pneumonia will also prevent against recurrent bacterial infections

Vaccination:

  • Hib and pneumococcal vaccination in HIV infected children less than 5 years of age will be highly recommended.
  • Administer all the routine bacterial vaccines.

Secondary prevention

  • TMP-SMX prophylaxis for patients with recurrent bacterial infections. [Recurrent bacterial infections is defined as 2 or more systemic bacterial infections including septicemia, meningitis, pneumonia and osteomyelitis that occur within a two-year period]
  • Intravenous Immunoglobulin [IVIg] at 400 mg/kg monthly for children with hypogammaglobulinemia if there are recurrent bacterial infections inspite of TMP-SMX prophylaxis.

Drugs & Dosage for of TMP-SMX

Drugs

Dosage

TMP/SMX

- 150 mg of TMP m2/day PO BD on alternate day

- 5 mg/kg of TMP/day PO HS daily



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