Congenital Toxoplasma
Loading

2 mg/kg/day on Day1 & 2
Continuation
1 mg/kg/day for 2-6 months and then 1mg/kg 3 times a week to complete 12 months
Acquired Toxoplasma
Loading

2 mg/kg/day for 3 days
Continuation
1 mg/kg/day for 6 weeks

Clindamycin

5-7.5 mg/kg/do PO 4 times daily
(max 600 mg/dose)

Fever rash, GI symptoms, Pseudomembranous colitis, hepatotoxicity

In patients hypersensitive to sulfonamide. Is given along with Pyrimethamine

Azithromycin

-

-

Used in adults with
Pyrimethamine in sulfa-
allergic patients

Atovaquone

-

-

Used in adults with
Pyrimethamine or

Sulphadiazine or as a single agent

TMP/SMX

5 mg/kg TMP
+ 25 mg/kg SMX
IV/PO BD

-

Not used in children. Used as alternative to
Pyrimethamine-Sulfadiazine in adults.